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Mood disorders are emotional disturbances which consist of prolonged periods of excessive sadness, excessive joyousness, or both. Mood disorders can occur in children and adolescents (see Depressive Disorders in Children and Adolescents). Examples of mood DOs are: Major depressive disorder — prolonged and persistent periods of extreme sadness. Bipolar disorder — also called manic depression or bipolar affective disorder, depression that includes alternating times of depression and mania.